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Other changes include: Lens distortion correction can be applied to multiple images in a stack Works with Creative Cloud Libraries Crop (if you have a supported camera connected) Vignette correction Lens flare compensation Auto exposure adjustment Lens adjustment for sharpness, distortion correction and softness Custom curve adjustments A new Quick Fix menu tab that contains a variety of quick fixes to common problems, including The Lens Fixer features a new Panel (Figure 1) that includes 2 sliders and a preview pane. The two sliders work like the ones on the Lens and Auto Adjust tools in the previous versions of Adobe Photoshop Elements, except the bottom slider is in the vertical direction, and the other is in the horizontal direction. When you drag a slider left or right, a preview will appear in the bottom part of the panel, and a live preview of the image will show up when you drop the mouse cursor on the preview pane (Figure 2). You can also turn off the live preview by pressing the Ctrl + D keyboard shortcut. Figure 1: Panel Control Sliders Figure 2: Preview Pane Customizable panel button bar You can now add, edit or remove panel buttons from the Tool Options dialog box and from the panel itself in the control bar (Figure 3). You can configure how the buttons will behave with a menu of options. You can choose from: Bold, Italic, Faded, Outline, Move, Scale, Rotate, Flip Horizontal or Flip Vertical Show/hide menu items Using the keyboard shortcut Option + the number of the button you want to configure, the button will highlight and the Show/Hide Menu will appear. Figure 3: Tool Options (Previous Versions Only) Rotate panel buttons You can now customize the rotation of the panel buttons and also remove some buttons (Figure 4). 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Choline level in the CSF was correlated inversely with the survival of ALS patients (r = -0.50, P = 0.007), but not with plasma free choline level. We conclude that plasma and CSF free choline levels are not lower in ALS patients than in control subjects. In addition, we found a significant correlation between the decline of choline level in the CSF and the survival time in ALS patients.Chemokines attract specific leukocyte subsets to sites of inflammation (1). Chemokines are small (8-14 kDa) proteins that signal through seven transmembrane-spanning G protein coupled receptors (2-3). The leukocyte subset that expresses each chemokine receptor is variable: CCR1 and CCR3 chemokine receptors are associated with monocytes, macrophages, dendritic cells, and T cells, whereas CCR5 and CXCR4 receptors are expressed on cells associated with HIV pathogenesis (T cell, monocyte, macrophage, dendritic cell, and endothelial cell) (4). 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